Inherited genetical disorders and reason of offsprings being different from parents

1.How do meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents? Be sure to talk about both meiosis and fertilization. 2. Describe one example of a human disorder that is inherited and also describe the specific inheritance pattern. For this question, pick disorders that result from mutations in DNA or chromosome number rather than examples such as a genetic tendency for a disorder such as cancer.